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Cruise ship in Panama Canal

Panama Canal Cruises from San Francisco

Four cruise lines offer cruises from San Francisco through the Panama Canal, an engineering marvel and the eighth wonder of the world. You'll pass through massive locks that lift or lower the ship. The area is also rich in exotic flora and fauna. The final destinations for these cruises from SF are in Florida. See the schedule of departures below.

The Panama Canal is a ship canal that connects the Pacific Ocean to the Atlantic. It is 48 miles long and is a vital route for international trade. Gatun Lake was created to reduce the amount of excavation required for the canal. The lake is 85 feet above sea level so locks at both ends raise and lower ships.

2021

17-day Panama Canal cruise on Norwegian Cruise Line. One-way from San Francisco to Miami (Florida). Visit San Diego (California), Cabo San Lucas (Mexico), Puerto Vallarta (Mexico), Puerto Quetzal (Guatemala), San Juan del Sur (Nicaragua), Puntarenas (Costa Rica), Panama City (Panama), the Panama Canal and Cartagena (Colombia).
• 2021 departure: October 28.

2022

15-day Panama Canal cruise on Princess Cruises. One-way from San Francisco to Fort Lauderdale (Florida). Visit Cabo San Lucas (Mexico), San Juan del Sur (Nicaragua), Puntarenas (Costa Rica), Fuerte Amador (Panama), the Panama Canal and Cartagena (Colombia).
• 2022 departure: February 25.

16-night Panama Canal cruise on Cunard Line. One-way from San Francisco to Fort Lauderdale (Florida). Visit Los Angeles (California), Cabo San Lucas (Mexico), Puntarenas (Costa Rica), the Panama Canal and Aruba.
• 2022 departure: July 24.

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