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Cruise ship in Panama Canal

Panama Canal Cruises from San Francisco

Three cruise lines offer cruises from San Francisco through the Panama Canal, an engineering marvel and the eighth wonder of the world. You'll pass through massive locks that lift or lower the ship. The area is also rich in exotic flora and fauna. The final destination for these cruises from SF is Florida or New York. See the schedule of departures below.

The Panama Canal is a ship canal that connects the Pacific Ocean to the Atlantic. It is 48 miles long and is a vital route for international trade. Gatun Lake was created to reduce the amount of excavation required for the canal. The lake is 85 feet above sea level so locks at both ends raise and lower ships.

2023

15-day Panama Canal cruise on Princess. One-way from San Francisco to Fort Lauderdale (Florida). Visit Cabo San Lucas (Mexico), San Juan del Sur (Nicaragua), Puntarenas (Costa Rica), Fuerte Amador (Panama), the Panama Canal and Cartagena (Colombia).
• 2023 departure: February 10.

20-day Panama Canal cruise on Oceania. One-way from San Francisco to New York. Visit Cabo San Lucas (Mexico), Ixtapa (Mexico), Puerto Quetzal (Guatemala), Corinto (Nicaragua), Puntarenas (Costa Rica), the Panama Canal, Cartagena (Colombia), Great Stirrup Cay (Bahamas), Miami (Florida) and Port Canaveral (Florida).
• 2023 departure: July 13.

16-night Panama Canal cruise on Cunard Line. One-way from San Francisco to Fort Lauderdale (Florida). Visit Los Angeles (California), Cabo San Lucas (Mexico), Puntarenas (Costa Rica), the Panama Canal and Aruba.
• 2023 departure: August 20.

19-day Panama Canal cruise on Norwegian. One-way from San Francisco to Miami (Florida). Visit Los Angeles (California), Cabo San Lucas (Mexico), Mazatlan (Mexico), Puerto Vallarta (Mexico), Acapulco (Mexico), Puerto Quetzal (Guatemala), Panama City (Panama), Cartagena (Colombia) and Grand Cayman (Cayman Islands).
• 2023 departure: October 31.

15-day Panama Canal cruise on Princess. One-way from San Francisco to Fort Lauderdale (Florida). Visit Cabo San Lucas (Mexico), San Juan del Sur (Nicaragua), Puntarenas (Costa Rica), Fuerte Amador (Panama), the Panama Canal and Cartagena (Colombia).
• 2023 departure: October 22.

2024

15-day Panama Canal cruise on Carnival. One-way from San Francisco to Galveston (Texas). Visit Cabo San Lucas (Mexico), Puntarenas (Costa Rica), the Panama Canal and Cartagena (Colombia).
• 2024 departure: October 1.

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