San Francisco Voyage
Cruises
Itineraries
Deals
Cruise ship in Panama Canal

Panama Canal Cruises from San Francisco

Three cruise lines offer cruises from San Francisco through the Panama Canal, an engineering marvel and the eighth wonder of the world. You'll pass through massive locks that lift or lower the ship. The area is also rich in exotic flora and fauna. The final destination for these cruises from SF is Florida or New York. See the schedule of departures below.

The Panama Canal is a ship canal that connects the Pacific Ocean to the Atlantic. It is 48 miles long and is a vital route for international trade. Gatun Lake was created to reduce the amount of excavation required for the canal. The lake is 85 feet above sea level so locks at both ends raise and lower ships.

2024

September 28, 2024: 16-day Panama Canal cruise on Princess. One-way from San Francisco to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Puerto Quetzal (Guatemala), Puntarenas (Costa Rica), Panama City (Panama), the Panama Canal, and Cartagena (Colombia).

October 1, 2024: 15-night Panama Canal cruise on Carnival. One-way from San Francisco to Galveston (Texas). Visit Cabo San Lucas (Mexico), Puntarenas (Costa Rica), the Panama Canal and Cartagena (Colombia).

2025

January 20, 2025: 16-night Panama Canal cruise on Princess. One-way from San Francisco to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Puerto Quetzal (Guatemala), Puntarenas (Costa Rica), Panama City (Panama), the Panama Canal, and Cartagena (Colombia).

June 6, 2025: 18-night Panama Canal cruise on Regent Seven Seas. One-way from San Francisco to Miami (Florida). Visit Los Angeles (California), Ensenada (Mexico), Cabo San Lucas (Mexico), Acapulco (Mexico), Puerto Quetzal (Guatemala), Corinto (Nicaragua), Puntarenas (Costa Rica), the Panama Canal, Cartagena (Colombia) and Grand Cayman (Cayman Islands).

October 6, 2025: 16-night Panama Canal cruise on Carnival. One-way from San Francisco to Galveston (Texas). Visit Cabo San Lucas (Mexico), Puntarenas (Costa Rica), the Panama Canal, Cartagena (Colombia) and Grand Cayman (Cayman Islands).

December 7, 2025: 16-night Panama Canal cruise on Princess. One-way from San Francisco to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Puerto Quetzal (Guatemala), Puntarenas (Costa Rica), Panama City (Panama), the Panama Canal, and Cartagena (Colombia).

Cruise Lines
Cruise Terminal
Site Map
About